e-nnovation Life Sciences in collaboration with GeneFirst brings you the proprietary technologies for detection of Human Papillomavirus (HPV) infection. Now, the test is available in Indian market at economical rates with convenient delivery time.

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Globally speaking Human papillomavirus (HPV) infection is the most common sexually transmitted infections.  The link between persistent infection and cervical cancer has led to the emergence of cancer screening programs to better stratify women and their risk of developing cervical cancer.  Over 150 HPV types have been identified, some of which have been associated as major risk factors in cervical cancer.  The clinical significance of persistence and clearance rates of virus over time on the severity and progression, as well as co-infection of high- and low-risk HPV types, have recently been identified as factors for disease progression.  However, the current HPV diagnostic tools are limited in their use for the detection, identification and differentiation of multiple HPV genotypes. 

 

The Papilloplex® High Risk HPV test has been designed to address these unmet medical needs by targeting 14 HPV genotypes to better stratify disease risk and progression.  This test, based on GeneFirst’s proprietary MPA Technology, aids our understanding of genotype-specific HPV infection in developing strategies to enhance the prevention and management of cervical cancer.  â€‹

 

Key Features and Benefits

·                     Simultaneous detection and differentiation of all high-risk types including 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68

·         DNA test for better sensitivity and risk stratification

·         Internal control for sample cellularity and PCR inhibition

·         Ease-of-use in a single, multiplex, real-time PCR reaction

·         Flexible, customisable throughput

 

TECHNICAL SPECIFICATION 

Parameters

Technical Specifications

Target sequence

L1 Region

Specificity range

95% to 100% for all genotypes covered

Limit of detection

100 copies for HPV types 16 and 18

Extraction/Inhibition control

Internal human DNA confirming absence of PCR inhibitors, sample adequacy and quality of DNA extraction

Validated sample type

Cervical (Thinprep), Urine

Validated extraction system

NucliSENS® easyMAG®, QIAamp® DNA Mini Kit 

Validated amplification system

Applied Biosystems® 7500

Kit storage

-20°C